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USA	Editor Profile Chao Chen Associate Editor Central South University Email: chenchao@sklmg.edu.cn

Chao Chen

China

Specialty Area

Psychiatric genetics; Genomics and epigenomics; Bioinformatics.

Editor introduction

Dr. Chen is an associate professor of Central South University. Dr. Chen has published a total of more than 20 papers in SCI, cited 600 times more, and a single reference is up to more than 200 times. His research focus on integrating diverse data (e.g. genetic, epigenetic, transcriptomic, proteomic data and etc.) into graphic networks, and analyzing next generation sequencing data for elucidating complex mechanisms of psychiatric disorders, which include 1) method development in integrating diverse high-throughput data into high-dimensional/probabilistic causal network models; 2) QTL studies of epigenetic traits in human brain; 3) method development to interpret microarray and next generation sequencing data.

Selected Scholarly Contributions

1. Genome-wide DNA Methylation Changes Associated with Intermittent Explosive Disorder: A Gene-Based Functional Enrichment Analysis, Int J Neuropsychopharmacol, 2017 Nov 2.

2. Analysis copy number variation of Chinese children in early-onset epileptic encephalopathies with unknown cause, Clin Genet. 2016 Nov; 90(5): 428-436.

3. The use of targeted genomic capture and massively parallel sequencing in diagnosis of Chinese Leukoencephalopathies, Sci Rep, 2016 Oct 25; 6: 35936.

4. Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia, Bipolar Disorders, 2014; 16(8): 790-799.

5. Two gene co-expression modules differentiate psychotics and controls, Mol Psychiatry, 2013 Dec; 18(12): 1308-1314.

6. The evolutionary relationship between microbial rhodopsins and metazoan rhodopsins, Scientific World Journal, 2013; 2013: 435651.

7. Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants, Molecular Psychiatry, 2013 Mar; 18(3): 340-346.

8. Removing batch effects in analysis of expression microarray data: an evaluation of six batch adjustment methods, PLoS ONE, 2011 Feb 28; 6(2):e17238.

9. Principal component analyses in anthropological genetics, Advances in Anthropology, 2011; 1: 9-14.

Editor Profile

Chao Chen

Chao Chen

Specialty Area

Editor introduction

Selected Scholarly Contributions