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Negative Reports

A Section of Journal of Psychiatry and Brain Science

Topic Editors

Professor Elliot S. Gershon

Professor Elliot S. Gershon

Foundations Fund Professor of Psychiatry and Human Genetics, The University of Chicago

Professor Chunyu Liu

Professor Chunyu Liu

Department of Psychiatry, SUNY Upstate Medical University

Topical Collection Information

Dear Colleagues,

The importance of negative results from well-designed experiments is widely recognized in science. This is particularly true in human studies, where there have been repeated issues of non-replication of statistically significant results, as reviewed and analyzed by John P.A. Ioannidis. A paper on “Top 10 Replicated Findings from Behavioral Genetics” by Robert Plomin et al. is a useful example of how difficult it can be to assemble all the negative results on important topics in behavior and related neurobiology.

The Journal of Psychiatry and Brain Science (JPBS) has decided to contribute to the problems of replicability in our areas of interest, by publishing papers with critically designed experiments, high quality execution and analysis, and negative results. Clinical trials in psychiatry and neurology, genetic analyses, neurobiological studies, and animal models of psychiatric disorders, would be areas of particular interest. We will also publish meta-analyses related to reproducibility issues, and articles on experimental design and analysis related to reproducibility.

The negative reports should follow this structure:

Introduction: Define the purpose of the negative report and its significance. Relevant literature should be reviewed and controversial findings should be cited.

Materials and Methods

This section should describe in detail how the study was conducted, including:

Virtual Special Issues

•Study Design
•Experimental Procedures
•Data Analysis: Graphical and Tabular Displays for Analysis


Discussion: A perspective on the results presented, including statistical power of this study and of the known other studies.

Elliot S. Gershon
Chunyu Liu

Topic Editors

Online Submission

Manuscripts should be submitted online through Hapres Online Submission System. Please visit Guide for Authors before submitting a manuscript. Authors are encouraged to submit a paper as soon as it is ready and don’t need to wait until the deadline. Submissions will be sent to peer-review in order of arrival. Accepted papers will be published continuously in Journal of Psychiatry and Brain Science and then gathered together on the special issue webpage. We welcome Research articles, Review papers and Short Communications. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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